Hilmy Irsyadi Hanif  

Department of Oral Biology, Master’s Program of Dental Science, Faculty of Dentistry, Universitas Gadjah Mada, Indonesia, Oral and Maxillofacial Pathology Department, Faculty of Dental Medicine, Universitas Airlangga, Indonesia  

Bernedetta Esti Chrismawaty  

Department of Oral Medicine, Faculty of Dentistry, Universitas Gadjah Mada, Indonesia

DOI: https://doi.org/10.19184/stoma.v22i1.53690

ABSTRACT 

Psychological illnesses have been shown to induce lesions and symptoms in the oral cavity. Psychiatric patients frequently exhibit oral diseases characterized by clinical indicators and poor oral hygiene, linked to genetic and metabolic alterations in oral tissue, which coincide with psycho-neurological changes as contributing factors. The psychosomatic etiologies in oral diseases induce epigenetic alterations that can be chosen as the biomarker of pathologic condition. microRNA (miRNA/miR) plays crucial role in biological processes. Psychosomatic etiologies in oral diseases induce epigenetic alterations that may serve as biomarkers for pathological conditions. MicroRNA (miRNA/miR) plays a critical role in biological processes. Sixteen studies were selected based on their relevance to the topic and novelty. MiRNA expression is regulated and has been found to be associated with psychological disorders that cause oral manifestations. This study investigates the potential biomarker role of miRNAs expressed in oral diseases associated with psychological disorders.